Relationship between gut microbiome and allergic asthma

Since the late 20th century, environmental exposure to endotoxins has been very low and type I allergic disease increased. In addition, we have increased PM2.5 other chemicals. Recently, there is concern that daily use of hygiene products containing antimicrobial substances associated with an prevalence allergies. It noted these may exacerbate our study, confirmed intratracheal administration aqueous mite solution as inhaled antigen substance aggravating chemical induced much stronger bronchial asthma in mice than received alone. Thus, allergies found be exacerbated by simultaneous both antigens man-made chemicals (adjuvants). Next, analyzed 16S rRNA gut microbiota triclosan-treated developed allergy. The bacterial gene abundance Deltaproteobacteria, Erysipelotrichi Clostridia was a dose-dependent manner mice, while Bacteroides were decreased mice. composition altered after triclosan treatment correlated exacerbation asthmatic conclusion, because condition given drink, this increase or decrease certain bacteria gut, suspect if allergy sufferers continue triclosan, they will inhale dust mites house on basis, which aggravate their symptoms. Overall, overuse antimicrobials preservatives current life risks further increasing number patients. authors believe it time rethink lifestyle.